CD25分子
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CD25 分子
CD25
常用单克隆抗体或代号: TAC,7G7/B6;(IL- 2Ra )
主要表达细胞: Pre- T,Ta,Ba,Ma [CR]
分子质量(kDa)和结构: gp55(含2个CCP结构域)
功 能: 组成高亲力IL- 2受体,T细胞生长
CD25
Aka IL-2 receptor alpha chain, exists in at least 3 forms
Limited expression may safeguard against catastrophic T-cell proliferation by immunogenic stimulus.
Positive staining: Activated B, T, macrophages
Positive staining (disease): hairy cell leukemia