【求助】请教如何判断一段序列是否可能为microRNA前体呢？
丁香园论坛
1471
用什么办法能预测出来呢？谢谢!
UCSC genome browser - genes and gene predication tracks - sno/miRNA track
Description
This track displays positions of four different types of RNA in the human genome:
precursor forms of microRNAs (pre-miRNAs)
C/D box small nucleolar RNAs (C/D box snoRNAs)
H/ACA box snoRNAs
small Cajal body-specific RNAs (scaRNAs)
C/D box and H/ACA box snoRNAs are guides for the 2'O-ribose methylation and the pseudouridilation, respectively, of rRNAs and snRNAs, although many of them have no documented target RNA. The scaRNAs guide modifications of the spliceosomal snRNAs transcribed by RNA polymerase II, and often contain both C/D and H/ACA domains.
The pre-miRNA data are from the miRBase Sequence Database at the Wellcome Trust Sanger Institute. The snoRNA and scaRNA data are from snoRNABase, which is maintained at the Laboratoire de Biologie Moléculaire Eucaryote.
Description
This track displays positions of four different types of RNA in the human genome:
precursor forms of microRNAs (pre-miRNAs)
C/D box small nucleolar RNAs (C/D box snoRNAs)
H/ACA box snoRNAs
small Cajal body-specific RNAs (scaRNAs)
C/D box and H/ACA box snoRNAs are guides for the 2'O-ribose methylation and the pseudouridilation, respectively, of rRNAs and snRNAs, although many of them have no documented target RNA. The scaRNAs guide modifications of the spliceosomal snRNAs transcribed by RNA polymerase II, and often contain both C/D and H/ACA domains.
The pre-miRNA data are from the miRBase Sequence Database at the Wellcome Trust Sanger Institute. The snoRNA and scaRNA data are from snoRNABase, which is maintained at the Laboratoire de Biologie Moléculaire Eucaryote.
多谢楼上指教！
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