ABER在位活细胞分析的运用
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ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA">原位活细胞在线检测仪ABER 能实时在线检测发酵罐内活细胞的浓度,密度,干重,生物量体积,电容大小,导电率大小;而不受细胞碎片,细胞团块,死细胞,发酵液泡沫,微载体颗粒等影响。
适用范围: 动植物细胞,酵母,细菌藻类等种类的研究和生产质量控制。广泛适用于发酵生产工艺中的质量控制。符合 ISO,FDA, cGMP 等认证。
微载体培养监测: Monitoring CHO cells with the Biomass Monitor using microcarrier culture (upper graph data courtesy of Genzyme Inc) and suspension culture (data courtesy of GSK)
在线过程控制: Schematic of a perfusion bioreactor with an Aber ViableCell Monitor (VCM) and acoustic filter. In the control algorithm, a cell specific perfusion rate is specified and the biomass density signalis averaged and converted to a perfusion flow rate.Unpublished data c-ourtesy of J.E. Dowd (JEHD Consulting).
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