Tissue-Specific Delivery of an anti-H-ras Ribozyme Against Malignant Melanoma
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Malignant melanoma is an increasingly important clinical problem in the United States, because the incidence of cutaneous malignant melanoma has been increasing significantly in recent years (1 ,2 ) Despite the use of cancer chemotherapy and immunotherapy for treatment against the advanced stages of malignant melanoma, the prognosis still remains poor (3 –5 ).
