Polynucleotide Kinase (EC 2.7.1.78)
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The enzyme polynucleotide kinase (PNK, or ATP:5′-dephospho-polynucleotide 5′-phosphatase) catalyzes the transfer of a γ-phosphate group from a 5′-nucleoside triphosphate moiety to a free 5′-hydroxyl of a polynucleotide such as DNA or RNA, to form a 5′-phosphorylated DNA or RNA molecule and a nucleoside diphosphate.
![tert-butyl 3-(7-chloro-8-fluoro-5-methoxy-2-methylsulfanyl-pyrido[4,3-d]pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octane-8-carboxylate，2763158-78-5，阿拉丁](https://img1.dxycdn.com/p/s14/2024/0619/324/2369665668294523081.jpg!wh200)
