丁香实验_LOGO
登录
提问
我要登录
|免费注册
点赞
收藏
wx-share
分享

CD46分子

互联网

2046
CD46 分子
 
CD46
常用单克隆抗体或代号: HULYM5,J48
主要表达细胞: 广泛,Leu,Pt [NL]
分子质量(kDa)和结构: gp56- 66,膜辅助因子蛋白(MCP)
功    能: 调节补体活化,裂解C3b ,C4b膜辅助因子蛋白
 
CD46
Aka membrane cofactor protein (MCP)
Cofactor for Factor I proteolytic cleavage of C3b and C4b; prevents inappropriate complement activation, especially via alternative pathway, by limiting formation and function of C3 convertases
Receptor for measles virus and HHV-6
Has multiple isoforms
Acrosomal CD46 is exposed on sperm head at capacitation; may help fuse spermatozoa and oocyte
Positive staining (normal): all cells except erythrocytes

 
提问
扫一扫
丁香实验小程序二维码
实验小助手
丁香实验公众号二维码
扫码领资料
反馈
TOP
打开小程序