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Genetic Transformation of Candida albicans

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Genetic transformation is the primary method of genetic manipulation of Candida albicans . The lack of a complete sexual cycle prevents application of classical genetic analyses. However, transformation permits introduction into the genome of a wide variety of defined mutations including deletions, insertions, and fusions. Although several methods of transformation are available, the lithium-cation-induced transformation method described here is the most commonly used.
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