Molecular Modeling of Nucleic Acid Structure
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- Abstract
- Table of Contents
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- Literature Cited
Abstract
This unit is the first in a series of four units covering the analysis of nucleic acid structure by molecular modeling. The unit provides an overview of the computer simulation of nucleic acids. Topics include the static structure model, computational graphics and energy models, the generation of an initial model, and characterization of the overall three?dimensional structure. Curr. Protoc. Nucleic Acid Chem . 54:7.5.1?7.5.13. © 2013 by John Wiley & Sons, Inc.
Keywords: nucleic acid chemistry; nucleic acid structure and folding; structural analysis of biomolecules; experimental determination of structure; folding and conformational change
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- Introduction
- Molecular Modeling
- Summary
- Literature Cited
- Figures
- Tables
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Figure 7.5.1 Schematic representation of molecular modeling analysis. View Image -
Figure 7.5.2 Canonical structures of DNA built with the Nucleic Acid Builder program available in Amber12 (see Macke and Case, , for a description of the program). View Image -
Figure 7.5.3 Pictorial definition of helicoidal parameters. View Image
Videos
Literature Cited
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