Treatment of Liver Malignancies with Electrochemotherapy in a Rat Model

Electrochemotherapy (ECT) is a combination treatment which involves administering a chemotherapeutic agent followed by the delivery of electric pulses to cells or tissue. Electrical treatment results in increased drug uptake by the cells which provides an improved therapeutic benefit relative to using the drug alone. Increased drug uptake is due to a process that has been termed electropermeabilization, or electroporation.