Immunoassay Measurements of Leptin

Since the discovery of the circulating peptide hormone, leptin, the recognition of adipose tissue (AT) as an endocrine organ has added a new perspective to obesity research. Numerous studies have shown the involvement of leptin (expressed predominantly in AT, placenta, and stomach) in the physiology of hematopoiesis, immune function, angiogenesis, fertility and the regulation of body wt (1 ).