2003年Nucleic Acids Research最热门文章集锦
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Nucleic Acids Research是做生物信息学和分子生物学必读的文章，许多文章本身就是经典的protocol，这里收集2003年最热门的文章，希望大家能喜欢，这里包括最热门的文章，最热门的数据库，最热门的方法学文章，以及Nucleic Acids Research上自从创立以来阅读最多的文章。
TOP STANDARD CATEGORY PAPERS, 2003
Short hairpin type of dsRNAs that are controlled by tRNAVal promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
Hiroaki Kawasaki and Kazunari Taira
Nucleic Acids Research (2003), 31, 700-707 abstract full text
siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells
Hiroaki Kawasaki, Eigo Suyama, Mayu Iyo, and Kazunari Taira
Nucleic Acids Research (2003), 31, 981-987 abstract full text
Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA
Frank Czauderna, Melanie Fechtner, Hüseyin Aygün, Wolfgang Arnold, Anke Klippel, Klaus Giese, and Jörg Kaufmann
Nucleic Acids Research (2003), 31, 670-682 abstract full text
TOP METHODS PAPERS, 2003
Summaries of Affymetrix GeneChip probe level data
Rafael A. Irizarry, Benjamin M. Bolstad, Francois Collin, Leslie M. Cope, Bridget Hobbs, and Terence P. Speed
Nucleic Acids Research (2003), 31, e15 abstract full text
A simple and cost-effective method for producing small interfering RNAs with high efficacy
Muhammad Sohail, Graeme Doran, Johann Riedemann, Val Macaulay, and Edwin M. Southern
Nucleic Acids Research (2003), 31, e38 abstract full text
Establishment of conditional vectors for hairpin siRNA knockdowns
Shiro Matsukura, Peter A. Jones, and Daiya Takai
Nucleic Acids Research (2003), 31, e77 abstract full text
TOP DATABASE ISSUE PAPERS, 2003
The Molecular Biology Database Collection: 2003 update
Andreas D. Baxevanis
Nucleic Acids Research (2003), 31, 1-12 abstract full text
Ensembl 2002: accommodating comparative genomics
M. Clamp, D. Andrews, D. Barker, P. Bevan, G. Cameron, Y. Chen, L. Clark, T. Cox, J. Cuff, V. Curwen, T. Down, R. Durbin, E. Eyras, J. Gilbert, M. Hammond, T. Hubbard, A. Kasprzyk, D. Keefe, H. Lehvaslaiho, V. Iyer, C. Melsopp, E. Mongin, R. Pettett, S. Potter, A. Rust, E. Schmidt, S. Searle, G. Slater, J. Smith, W. Spooner, A. Stabenau, J. Stalker, E. Stupka, A. Ureta-Vidal, I. Vastrik, and E. Birney
Nucleic Acids Research (2003), 31, 38-42 abstract full text
Database resources of the National Center for Biotechnology
David L. Wheeler, Deanna M. Church, Scott Federhen, Alex E. Lash, Thomas L. Madden, Joan U. Pontius, Gregory D. Schuler, Lynn M. Schriml, Edwin Sequeira, Tatiana A. Tatusova, and Lukas Wagner
Nucleic Acids Research (2003), 31, 28-33 abstract full text
TOP WEB SERVER ISSUE PAPERS, 2003
Mfold web server for nucleic acid folding and hybridization prediction
Michael Zuker
Nucleic Acids Research (2003), 31, 3406-3415 abstract full text
SWISS-MODEL: an automated protein homology-modeling server
Torsten Schwede, Jürgen Kopp, Nicolas Guex, and Manuel C. Peitsch
Nucleic Acids Research (2003), 31, 3381-3385 abstract full text
GenePublisher: automated analysis of DNA microarray data
Steen Knudsen, Christopher Workman, Thomas Sicheritz-Ponten, and Carsten Friis
Nucleic Acids Research (2003), 31, 3471-3476 abstract full text
TOP PAPERS FROM PREVIOUS YEARS
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
S. F. Altschul, T. L. Madden, A. A. Schaffer, J. Zhang, Z. Zhang, W. Miller, D. J. Lipman
Nucleic Acids Research (1997), 25, 3389-3402 abstract full text
The Protein Data Bank
Helen M. Berman, John Westbrook, Zukang Feng, Gary Gilliland, T. N. Bhat, Helge Weissig, Ilya N. Shindyalov, Philip E. Bourne
Nucleic Acids Research (2000), 28, 235-242 abstract full text
The Pfam Protein Families Database
Alex Bateman, Ewan Birney, Lorenzo Cerruti, Richard Durbin, Laurence Etwiller, Sean R. Eddy, Sam Griffiths-Jones, Kevin L. Howe, Mhairi Marshall, and Erik L. L. Sonnhammer
Nucleic Acids Research (2002), 30, 279-280 abstract full text
The Ensembl genome database project
T. Hubbard, D. Barker, E. Birney, G. Cameron, Y. Chen, L. Clark, T. Cox, J. Cuff, V. Curwen, T. Down, R. Durbin, E. Eyras, J. Gilbert, M. Hammond, L. Huminiecki, A. Kasprzyk, H. Lehvaslaiho, P. Lijnzaad, C. Melsopp, E. Mongin, R. Pettett, M. Pocock, S. Potter, A. Rust, E. Schmidt, S. Searle, G. Slater, J. Smith, W. Spooner, A. Stabenau, J. Stalker, E. Stupka, A. Ureta-Vidal, I. Vastrik, and M. Clamp
Nucleic Acids Research (2002), 30, 38-41 abstract full text
Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation
Yee Hwa Yang, Sandrine Dudoit, Percy Luu, David M. Lin, Vivian Peng, John Ngai, and Terence P. Speed
Nucleic Acids Research (2002), 30, e15 abstract full text
AFLP: a new technique for DNA fingerprinting
P. Vos, R. Hogers, M. Bleeker, M. Reijans, T. van de Lee, M. Hornes, A. Frijters, J. Pot, J. Peleman, M. Kuiper
Nucleic Acids Research (1995), 23, 4407-4414 abstract
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
J. D. Thompson, D. G. Higgins, T. J. Gibson
Nucleic Acids Research (1994), 22, 4673-4680 abstract
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
J. D. Dignam, R. M. Lebovitz, R. G. Roeder
Nucleic Acids Research (1983), 11, 1475-1489 abstract
(转自生物谷）
TOP STANDARD CATEGORY PAPERS, 2003
Short hairpin type of dsRNAs that are controlled by tRNAVal promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
Hiroaki Kawasaki and Kazunari Taira
Nucleic Acids Research (2003), 31, 700-707 abstract full text
siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells
Hiroaki Kawasaki, Eigo Suyama, Mayu Iyo, and Kazunari Taira
Nucleic Acids Research (2003), 31, 981-987 abstract full text
Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA
Frank Czauderna, Melanie Fechtner, Hüseyin Aygün, Wolfgang Arnold, Anke Klippel, Klaus Giese, and Jörg Kaufmann
Nucleic Acids Research (2003), 31, 670-682 abstract full text
TOP METHODS PAPERS, 2003
Summaries of Affymetrix GeneChip probe level data
Rafael A. Irizarry, Benjamin M. Bolstad, Francois Collin, Leslie M. Cope, Bridget Hobbs, and Terence P. Speed
Nucleic Acids Research (2003), 31, e15 abstract full text
A simple and cost-effective method for producing small interfering RNAs with high efficacy
Muhammad Sohail, Graeme Doran, Johann Riedemann, Val Macaulay, and Edwin M. Southern
Nucleic Acids Research (2003), 31, e38 abstract full text
Establishment of conditional vectors for hairpin siRNA knockdowns
Shiro Matsukura, Peter A. Jones, and Daiya Takai
Nucleic Acids Research (2003), 31, e77 abstract full text
TOP DATABASE ISSUE PAPERS, 2003
The Molecular Biology Database Collection: 2003 update
Andreas D. Baxevanis
Nucleic Acids Research (2003), 31, 1-12 abstract full text
Ensembl 2002: accommodating comparative genomics
M. Clamp, D. Andrews, D. Barker, P. Bevan, G. Cameron, Y. Chen, L. Clark, T. Cox, J. Cuff, V. Curwen, T. Down, R. Durbin, E. Eyras, J. Gilbert, M. Hammond, T. Hubbard, A. Kasprzyk, D. Keefe, H. Lehvaslaiho, V. Iyer, C. Melsopp, E. Mongin, R. Pettett, S. Potter, A. Rust, E. Schmidt, S. Searle, G. Slater, J. Smith, W. Spooner, A. Stabenau, J. Stalker, E. Stupka, A. Ureta-Vidal, I. Vastrik, and E. Birney
Nucleic Acids Research (2003), 31, 38-42 abstract full text
Database resources of the National Center for Biotechnology
David L. Wheeler, Deanna M. Church, Scott Federhen, Alex E. Lash, Thomas L. Madden, Joan U. Pontius, Gregory D. Schuler, Lynn M. Schriml, Edwin Sequeira, Tatiana A. Tatusova, and Lukas Wagner
Nucleic Acids Research (2003), 31, 28-33 abstract full text
TOP WEB SERVER ISSUE PAPERS, 2003
Mfold web server for nucleic acid folding and hybridization prediction
Michael Zuker
Nucleic Acids Research (2003), 31, 3406-3415 abstract full text
SWISS-MODEL: an automated protein homology-modeling server
Torsten Schwede, Jürgen Kopp, Nicolas Guex, and Manuel C. Peitsch
Nucleic Acids Research (2003), 31, 3381-3385 abstract full text
GenePublisher: automated analysis of DNA microarray data
Steen Knudsen, Christopher Workman, Thomas Sicheritz-Ponten, and Carsten Friis
Nucleic Acids Research (2003), 31, 3471-3476 abstract full text
TOP PAPERS FROM PREVIOUS YEARS
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
S. F. Altschul, T. L. Madden, A. A. Schaffer, J. Zhang, Z. Zhang, W. Miller, D. J. Lipman
Nucleic Acids Research (1997), 25, 3389-3402 abstract full text
The Protein Data Bank
Helen M. Berman, John Westbrook, Zukang Feng, Gary Gilliland, T. N. Bhat, Helge Weissig, Ilya N. Shindyalov, Philip E. Bourne
Nucleic Acids Research (2000), 28, 235-242 abstract full text
The Pfam Protein Families Database
Alex Bateman, Ewan Birney, Lorenzo Cerruti, Richard Durbin, Laurence Etwiller, Sean R. Eddy, Sam Griffiths-Jones, Kevin L. Howe, Mhairi Marshall, and Erik L. L. Sonnhammer
Nucleic Acids Research (2002), 30, 279-280 abstract full text
The Ensembl genome database project
T. Hubbard, D. Barker, E. Birney, G. Cameron, Y. Chen, L. Clark, T. Cox, J. Cuff, V. Curwen, T. Down, R. Durbin, E. Eyras, J. Gilbert, M. Hammond, L. Huminiecki, A. Kasprzyk, H. Lehvaslaiho, P. Lijnzaad, C. Melsopp, E. Mongin, R. Pettett, M. Pocock, S. Potter, A. Rust, E. Schmidt, S. Searle, G. Slater, J. Smith, W. Spooner, A. Stabenau, J. Stalker, E. Stupka, A. Ureta-Vidal, I. Vastrik, and M. Clamp
Nucleic Acids Research (2002), 30, 38-41 abstract full text
Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation
Yee Hwa Yang, Sandrine Dudoit, Percy Luu, David M. Lin, Vivian Peng, John Ngai, and Terence P. Speed
Nucleic Acids Research (2002), 30, e15 abstract full text
AFLP: a new technique for DNA fingerprinting
P. Vos, R. Hogers, M. Bleeker, M. Reijans, T. van de Lee, M. Hornes, A. Frijters, J. Pot, J. Peleman, M. Kuiper
Nucleic Acids Research (1995), 23, 4407-4414 abstract
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
J. D. Thompson, D. G. Higgins, T. J. Gibson
Nucleic Acids Research (1994), 22, 4673-4680 abstract
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
J. D. Dignam, R. M. Lebovitz, R. G. Roeder
Nucleic Acids Research (1983), 11, 1475-1489 abstract
(转自生物谷）
