Animal Models of Cystitis

As in other areas of biomedical research, studies of bladder pathology rely heavily in animal models of cystitis. These can be basically divided in two types: induced by systemically administration and locally induced by challenge with immunogens or irritants. The choice between models is not easy, and several factors must be taken into account, namely side effects, intensity of the pathology, simplicity, and/or reproducibility of the method.