胰岛素受体信号通路（5张）

胰岛素受体信号通路

The appropriate signaling through the insulin pathway is critical for the regulation of glucose levels and the avoidance of diabetes. Insulin forms a complex with the Insulin Receptor (IR) and b chains to form the active signaling complex. Through recruitment of adaptor molecules and the activation of RAS, the activated IR can cause transcriptional activation.

Insulin receptor signaling pathway

AMPK参与葡萄糖代谢病与胰岛素信号通路联系

Insulin receptor signaling pathway

胰岛素信号通路的多样性

Pleiotropic insulin signaling pathways. CAP—c-Cbl-associated protein; IRS-1—insulin receptor substrate-1; MAPK—mitogenactivated protein kinase; PC-1—plasma Cell glycoprotein-1; PDK—phosphoinositide-dependent kinase; PKC—protein kinase C; PI3-K—phosphatidylinositol 3-kinase