Extraction of Ancient DNA
互联网
319
The DNA extraction process represents one of the critical stages in the analysis of degraded or ancient DNA. If polymerase chain reaction (PCR) amplification starts from a poor extract containing low template quantities, stochastic variation in the amplification of individual alleles may lead to allelic dropout (1 ), resulting in a high risk of false-homozygous typing of a heterozygous sample (2 ).