Morphological Assessment of Intracerebral Hemorrhage

Intracerebral hemorrhage (ICH) is a common and often fatal subtype of stroke and produces severe neurologic deficits in survivors, and several animal models of ICH have been developed. We have established the ICH models in mice, rats and pigs (1–4). This chapter introduces methods for assessing �morphological changes after ICH including early brain swelling and delayed brain atrophy.