Development of Anti-Inflammatory Drugs for Cardiovascular Disease

Cardiovascular disease is the leading cause of death in the United States. One in three men and one in ten women develop severe cardiovascular disease before the age of 60, resulting in health expenditures of over $100 billion per year. Even though cardiovascular disease primarily affects people advanced in age, disease progression begins early. Initiation of atherogenesis via formation of fatty streaks can occur as early as infancy (1 ).