Accelerated Solvent Extraction for Natural Products Isolation

Accelerated solvent extraction (ASE^� ), first introduced in 1995, is an automated rapid extraction technique that utilizes common solvents at elevated temperature and pressure, and thereby increases the efficiency of extraction of organic compounds from solid and semisolid matrices. ASE^� allows extractions for sample sizes 1–100 g in minutes, reduces solvent uses dramatically, and can be applied to a wide range of matrices, including natural products.