Generation of Murine Bone-Marrow-Derived Dendritic Cells
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Dendritic cells (DC) are the most potent antigen-presenting cells (APC) of the immune system. Derived from stem cells in the bone marrow, DC migrate to the tissues where they become “sentinels” of the immune system. DC possess the unique ability to initiate primary T-cell responses and can also stimulate and modulate both B and T lymphocytes during an ongoing immune response (1 -3 ).
