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Three-Dimensional Organ Culture Systems

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Normal brain functions are to the highest degree dependent on the cytoarchitecture and the intercellular relationships that govern both the nervous system metabolism (for instance, the integrity of the blood-brain barrier) and specific functions (synaptic transmission, glioneuronal relationships). Thus, the study of the biology of the nerve cells should be approached using experimental designs that preserve the histological structure in which these cells take part in vivo.
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