Chiral Separations by Capillary Electrophoresis Using Cinchona Alkaloid Derivatives as Chiral Counter-Ions
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Cinchona alkaloids and derivatives thereof, obtained by dedicated structural modifications, have a long tradition in various stereochemical methods. Among them, their stereoselective ion-pairing capabilities for acidic compounds have been exploited for capillary electrophoretic enantiomer separations of chiral acids (1 –14 ).
