Chiral Separation by HPLC With Pirkle-Type Chiral Stationary Phases
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Liquid chromatographic resolution of enantiomers on chiral stationary phases (CSPs) has been known as the most accurate and convenient means of determining the enantiomeric composition of chiral compounds including chiral drugs. As a result of significant effort devoted to the development of effective CSPs during the past decades, various CSPs are now available (1 –4 ).