Induction of Ca2+ Flux by Adhesion Molecules in Lymphocytes
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Integrins participate in numerous complex biological processes that include cell growth, differentiation, and migration, tissue organization and remodeling, inflammation, and immune response (1 ). Signals contributed by integrin-mediated cell adhesion cooperate with classical activatory receptors in initiating cellular activities, such as mitosis, secretion, or gene expression (2 ); by these means, cellular responses take into account all aspects of their environment.
