Evaluation of Individual-Cell Motility

The coordinated displacement of a cell is a highly complex process which relies on the integration of a series of signaling pathways and on the function of a large number of molecular components including all main structures of the cytoskeleton (1 ,2 ). Thus, a detailed knowledge of the regulation and function of the cytoskeleton is of central importance for the understanding of cell motility, and conversely, investigations of cell motility may shed light on the function of cytoskeletal components.