Cellulases as Chiral Selectors in Capillary Electrophoresis

The vast majority of proteins exercise their action by means of interaction with small molecules. These interactions are in most cases stereospecific, which is not surprising since the proteins themselves are chiral. As a useful consequence, proteins could have a potential as enantioselectors. This is immediately evident in the case of carrier/transport proteins, such as serum albumin (1 ) or α-1 acid glycoprotein (orosomucoid) (2 ), but also enzymes (3 ,4 ) bind their substrates and other ligands in a stereospecific way.