CD80分子
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CD80 分子
CD80
常用单克隆抗体或代号: B7- 1,BB1
主要表达细胞: Ba,Mac,TStr [B]
分子质量(kDa)和结构: gp60(IgSF)
功 能: 活化B细胞抗原,CD28、CTLA- 4配体,提供T细胞共刺激信号
CD80
Aka B7-1, BB1
Ligand for T cell marker CD28 or CTLA4 (CD152)
Co-regulator of T cell activation with CD86
Has critical role in autoimmune, humoral, and transplant responses
Positive staining (normal): activated B cells, T cells, macrophages, dendritic cells
Reference: 112203