CD85/CD85a/CD85b/CD85c/CD85d/CD85e/CD85f分子
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CD85/CD85a/CD85b/CD85c/CD85d/CD85e/CD85f 分子
CD85
常用单克隆抗体或代号：ILT／LIR家族
主要表达细胞：DC，B，PC，Tsub[DC]
分子质量(kDa)和结构：64―82(1SSF)
功 能：抑制或活化白细胞杀伤功能
CD85a
常用单克隆抗体或代号：ILT5／LIR3
主要表达细胞：M，Mac，G，Tsub，DC
CD85b
常用单克隆抗体或代号：Ⅱ-T8
CD85c
常用单克隆抗体或代号：LIR8
CD85d
常用单克隆抗体或代号：ILT4 LIR2，MIRl0
常用单克隆抗体或代号：G．DCsub，M
分子质量(kDa)和结构：110
CD85e
常用单克隆抗体或代号：ILT6／LIR4
CD85f
常用单克隆抗体或代号：ILTll
CD85
Summary: Marker of plasma cells and hairy cell leukemia
Aka LILRB1
ILT/LIR family
Inhibitory MHC class I receptor prevents killing by NK and T cells
Also inhibits B cells activated by antigen receptor and myelomonocytic cells activated by HLA-DR
Positive staining (normal): plasma cells (strong), mantle zone, germinal center B cells, T cell subset, NK cell subset; dendritic cells
Positive staining (disease): hairy cell leukemia (strong)
Reference: GeneCards
CD85a-ILT5/LIR3
CD85b-ILT8
CD85c-LIR8
CD85d-ILT4/LIR2, MIR10
CD85e-ILT6/LIR4
CD85f-ILT11
