Utilizing the Zebrafish Neurophenome Project (ZNP) Database for Analyses of Complex Neurophenotypes in Zebrafish Models
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As the rate of biomedical discovery is rising exponentially, electronic databases have become particularly effective in organizing
and sharing scientific knowledge. Due to a well-characterized genome, robust behavioral responses and physiological similarity
to humans, the zebrafish (Danio rerio
) has emerged as a useful species for neurobehavioral research. The growing utility of this model organism requires the development
of specialized databases of zebrafish neurophenotypes, such as the Zebrafish Neurophenome Project (ZNP) (http://www.tulane.edu/∼znpindex/search).
Representing a new bioinformatics-based tool, the ZNP interactive searchable database consolidates neurobehavioral and related
physiological phenotypes obtained in various zebrafish models and tests. This chapter outlines the contribution of the ZNP
to increased accessibility of current zebrafish neurobiological knowledge, and discusses how this database may be used for
various research projects.
