An In Vivo Model of Ischemia/Reperfusion and Inflammation of the Kidneys of the Rat

Renal failure is defined as the cessation of kidney function. Acute renal failure (ARF) involves the failure of the kidney over a period of hours or days and is potentially reversible, whereas chronic renal failure (CRF) develops over months or years and involves the irreversible destruction of kidney tissue by progressive renal disease(s) leading to endstage renal disease (ESRD).