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Random Oligonucleotide Mutagenesis

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Random oligonucleotide mutagenesis is a method to generate diversity that consists of incorporating random mutations, encoded on a synthetic oligonucleotide, into a specific region of a gene. The number of mutations in individual enzymes within the population can be controlled by varying the length of the target sequence and the degree of randomization during synthesis of the oligonucleotides.
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