CD33分子
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1972
CD33 分子
CD33
常用单克隆抗体或代号： MY9,H153,L4F3
主要表达细胞： My,BM [M]
分子质量(kDa)和结构： gp67(IgSF)
功 能： 参与造血
CD33
Myeloid cell antigen (also CD13); a sialoadhesin that may mediate cell-to-cell adhesion, acts as a receptor that inhibits the proliferation of normal and leukemic myeloid cells
Positive staining (normal): Precursor myeloid cells; most monocytic cells, epidermal Langerhans cells (variable)
Positive staining (disease): AML M1-M5 (75-85%), M7 (variable), CML (90%); blasts (all), some ALL
Negative staining: granulocytes, mature bone marrow cells, non-myeloid cells
