Assessment of Cognitive and Sensorimotor Deficits
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The behavioral tests described in this chapter provide a relatively comprehensive characterization of cognitive and/or sensorimotor
deficits in various rodent models of human neuropathology. Sensorimotor coordination (and unilateral deficits), general activity
levels, anxiety and depression-like behaviors, basic associative learning, relational learning, short-term memory, long-term
memory, and problem-solving strategy are among the domains that can be assessed with the data collected. After initial characterization
of the model, a subset of the tests may provide a more efficient battery for therapeutic studies using that model.