Chiral Separation by Capillary Electrophoresis Using Polysaccharides

Capillary electrophoresis (CE) offers numerous advantages, such as high separation efficiency, analysis speed, instrumentation simplicity, and reduced operating costs, compared with other separation analytical methods. One of the successful application areas of CE is in drug analysis, where the focus is on relatively small synthetic drugs. Various CE methods (modes) such as micellar electrokinetic chromatography (MEKC) and capillary gel electrophoresis (CGE) have been developed within CE techniques for the analysis of drugs. Among them, electrokinetic chromatography (EKC), including MEKC, and capillary zone electrophoresis (CZE) have been used for the separation of enantiomers.