Computational Methods for Identification of DNA Transposons

The initial identification of transposable elements (TEs) was attributed to the activity of DNA transposable elements, which are prevalent in plants. Unlike RNA elements, which accumulate in the gene-poor heterochromatic regions, most DNA elements are located in the gene rich regions and many of them carry genes or gene fragments. As such, DNA elements have a more intimate relationship with genes and may have an immediate impact on gene expression and gene function. DNA elements are structurally distinct from RNA elements and most of them have terminal inverted repeats (TIRs). Such structural features have been used to identify the relevant elements from genomic sequences. Among the DNA elements in plants, the most abundant type is the miniature inverted repeat transposable elements (MITEs). This chapter discusses the methods to identify MITEs, Helitron s, and other DNA transposable elements.