Overview of Informatics for High Content Screening

With the growing use of high content screening (HCS) and analysis in drug discovery and systems biology, informatics has come to the forefront as a critical technology to effectively utilize the massive volumes of high content data and images being generated. Informatics technologies are required to transform HCS data and images into useful information and then into knowledge to drive decision making in an efficient and cost effective manner. In this chapter, we provide an overview of informatics tools and technologies for HCS, discuss some of the challenges of harnessing the huge and growing volumes of HCS data, and provide insight to help toward implementing or selecting, and utilizing a high content informatics solution to meet your organization’s needs.