CD82分子
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CD82 分子
CD82
常用单克隆抗体或代号: 1A4,4F9;(R2)
主要表达细胞: Leu [B]
分子质量(kDa)和结构: gp50- 53(TM4-SF)
功 能: 淋巴细胞活化,信号传递
CD82
Aka prostate cancer antimetastasis gene KAI1, kang ai (Chinese for anticancer).
Metastasis suppressor gene; downregulated in tumor progression of cancers
Expression correlates with p53 expression
Associates with CD4 or CD8 and delivers costimulatory signals for T cell receptor pathway
Activation antigen for T cells
Positive staining (normal): activated/differentiated hemaoietic cells
Negative staining: erythrocytes
Reference: 600623