Algorithms for Calling Gains and Losses in Array CGH Data

In this chapter, we introduce a few statistical algorithms for calling gains and losses in array-based comparative genomic hybridization (array CGH) data, including CBS, CLAC, CGHseg, and Fused Lasso. We illustrate the performance of the methods through simulated and real data examples. We also provide brief guidance on how to use the corresponding software at the end of this chapter.