DNA and RNA Ligases (EC 6.5.1.1, EC 6.5.1.2, and EC 6.5.1.3)
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Ligases are a class of enzymes that catalyze the joining of nucleic acid molecules by the formation of phosphodiester bonds between their termini (1 ). The nucleic acid substrate to be linked may be DNA or RNA depending on the type of ligase involved.
