A Microscopic Model Calculation of the Phase Diagram of Ternary Mixtures of Cholesterol and Saturated and Unsaturated Phospholipids
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The authors solved a microscopic model that describes mixtures of a saturated phospholipid, an unsaturated phospholipid, and
cholesterol. The method employed was the self-consistent field approximation. The model was capable of producing several classes
of phase diagram, but only one of them showed a liquid-liquid coexistence region. The phospholipids in the cholesterol-rich
liquid are more ordered than those in the cholesterol-poor liquid. Within this model, coexistence of two liquids in the ternary
system is intimately tied to such coexistence in the binary cholesterol-saturated phospholipid system.