丁香实验_LOGO
登录
提问
我要登录
|免费注册
点赞
收藏
wx-share
分享

Colony Management

互联网

529
Technical advances in the generation of genetically modified (GM) mice and the efforts of large-scale consortia have provided a wealth of resources to the biomedical research community. It has never been easier to obtain a specifically modified allele. However, the establishment and production of GM mouse models using basic breeding methods can still present a unique set of challenges. This chapter aims to equip those new to mouse colony management with some valuable tools. Topics covered include basic reproduction and inheritance, welfare assessment, nomenclature, breeding schemes, and calculators for the production of desired genotypes. Breeding of transgenic founders or chimeras through the first generations is discussed as well as the influence of strain background on this process. Animal records management systems also play an important role in effective colony management.
提问
扫一扫
丁香实验小程序二维码
实验小助手
丁香实验公众号二维码
扫码领资料
反馈
TOP
打开小程序