Co-immunoprecipitation of Tumor Suppressor Protein-Interacting Proteins
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Tumor suppressor proteins, like most proteins, require interacting with other proteins in the cell to function properly. These interacting proteins may be regulators or substrates of this tumor suppressor protein. A tumor suppressor protein may also associate with its interacting proteins to form a functional complex to perform an activity. Identification and characterization of proteins that associate with a tumor suppressor protein can provide important information for the tumor suppressor’s function and how this function is regulated.
