CD26分子
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CD26 分子
CD26
常用单克隆抗体或代号： 5.9,Tal
主要表达细胞： Ta,Ba,Mac [NL]
分子质量(kDa)和结构： gp110
功 能： 二肽酰酶Ⅳ(DPPⅣ),HIV另一类受体,参与T细胞活化,腺苷脱氨酶结合蛋白
CD26
Aka dipeptidylpeptidase IV, adenosine deaminase complexing protein 2
Costimulatory molecule in T cell activation
Cofactor with CD4 for HIV entry into cells
Positive staining (normal): Activated T, B cells, NK cells, macrophages, renal proximal tubular epithelial cells, small intestinal epithelium, biliary canaliculae, splenic sinus lining cells
Negative/dim staining: T cells in peripheral blood of mycosis fungoides patients, AJCP 2001;115:885
