Radioligand Binding to Solubilized 5-HT3 Receptors

Most receptors, apart from those for steroid and thyroid hormones, are transmembrane glycoproteins and are generally expressed by tissues in relatively low quantities. Exceptions include the nicotinic acetylcholine receptor in Torpedo electric organs and the rhodopsin receptor in the retina, in which the abundance of these receptors aided their characterization much earlier than other receptors.