Mechanisms and Assessment of Mitogenesis: An Overview
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When Nowell (1
) used a preparation of phytohemagglutinin (PHA) to separate red and white blood cells (a procedure described a decade earlier
[2
]), the consequences were far-reaching for studies of both lectins and lymphocytes The key observation was that, in addition
to the expected agglutination of erythrocytes, lymphocytes were induced to grow and divide.
