丁香实验_LOGO
登录
提问
我要登录
|免费注册
点赞
收藏
wx-share
分享

Platelet Neutralization Test

互联网

468
The platelet neutralization test is used in the laboratorvy diagnosis of the lupus anticoagulant (Laffan and Manning, Dacie and Lewis practical haematology. Churchill Livingstone, Philadelphia, PA, pp 445–446, 2006). The lupus anticoagulant typically causes prolongation of phospholipid-dependent coagulation tests such as APTT, DRVVT, etc.
The phospholipid-dependent nature of the LA can be demonstrated by adding washed and “fractured” platelets as a source of phospholipid and repeating the tests. If an LA is present in the sample, the addition of platelets will correct the prolonged clotting times. This appears to be due to the ability of the platelets to absorb the LA and negate its effect on the clotting time (Br J Haematol 109:704–715, 2001).
提问
扫一扫
丁香实验小程序二维码
实验小助手
丁香实验公众号二维码
扫码领资料
反馈
TOP
打开小程序