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Haplotype Inference

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550
Haplotypes, as they specify linkage patterns between individual nucleotide variants, confer critical information for understanding the genetics of human diseases. However, haplotype information is not directly obtainable from high-throughput genotyping platforms. In this chapter, we introduce two representative methods to reconstruct haplotypes from unphased genotype data, one method is for unrelated individuals and the other is for families.
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