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Biomedical Applications of Proteomics
Published Online: 17 Sep 2004

Editor(s): Dr. Jean-Charles Sanchez, Dr. Garry L. Corthals, Prof. Dr. Denis F. Hochstrasser

Print ISBN: 3527308075 Online ISBN: 3527601562

Copyright © 2004 Wiley-VCH Verlag GmbH & Co. KGaA



Front Matter (p i-xxvii)

Introduction (p 1-4)
Prof. Dr. Denis F. Hochstrasser, Dr. Garry L. Corthals, Dr. Jean-Charles Sanchez

Part I: Aspects in Biomedical Research
Chapter 1:
Proteomics in Biomedicine - A Tool, a Science, or an Art? (p 5-15)
Prof. Marc A. Reymond

Part II: Blood Vessels
Chapter 2:
Antibody-Based Vascular Targeting: Proteomic Techniques for the Identification and Quantification of Membrane Proteins on Endothelial Cells (p 17-38)
Simone Scheurer, Jascha-Nikolai Rybak, Christoph Roesli, Dr. Giuliano Elia, Prof. Dr. Dario Neri

Chapter 3:
Vasculature, Vascular Disease, and Atherosclerosis (p 39-55)
Elisabetta Gianazza, Ivano Eberini

Chapter 4:
Discovery of New Diagnostic Markers of Stroke (p 57-72)
Dr. Laure Allard, Prof. Dr. Denis F. Hochstrasser, Dr. Jean-Charles Sanchez

Part III: Cancer
Chapter 5:
Unravelling Biological Pathways and the Identification of Clinical Markers and Targets in Renal Cancer (p 73-96)
Rosamonde E. Banks, Peter J. Selby

Chapter 6:
Heat Shock Protein 27 in Cancer (p 97-109)
Dr. Cecilia Sarto, Dr. Fulvio Magni, BS. Cristina Valsecchi, Prof. Dr. Paolo Mocarelli

Chapter 7:
Proteomic Approaches for Biomarker Discovery in Colorectal Cancer (p 111-131)
Prof. Dr. Richard J. Simpson, Dr. Donna S. Dorow

Chapter 8:
Clinical Proteomics: Ovarian Cancer (p 133-154)
Prof. Dr. Ayodele A. Alaiya

Chapter 9:
Protein Expression Profiling Analysis in Hematopoietic Stem Cells: Phenotypic Characterization of Mesenchymal Stem Cells (p 155-171)
Dr. Juan Antonio López, Dr. Antonio Bernad, Dr. Juan Pablo Albar

Chapter 10:
Lymphoblastoid and Lymphoma Cells (p 173-188)
Dr. Raymonde Joubert-Caron, Dr. Didier Lutomski, Dr. Michel Caron

Part IV: Pharmaco-Toxicology
Chapter 11:
Chemoresistance in Cancer Cells (p 189-204)
Dr. Julia Poland, Prof. Dr. Dirk Schadendorf, Dr. Hermann Lage, Prof. Dr. Pranav Sinha

Part 4: Immunogenicity of Apoptotic Cells
Chapter 12:
Diabetes Mellitus: Complex Molecular Alterations (p 205-223)
Gerhard Schmid, Dr. Jean-Charles Sanchez

Part V: Infectious Diseases
Chapter 13:
Proteome Approach to Infectious Diseases: Acute-Phase Proteins and Antibody Profiles as Diagnostic Indicators in Human Plasma (p 225-243)
Dr. Luca Bini, Dr. Sabrina Liberatori, Prof. Dr. Vitaliano Pallini

Chapter 14:
Proteomic Studies of Human Lymphocytes: New Insights into HIV Lymphocyte Infection? (p 245-262)
Dr. Françoise Vuadens, David Crettaz, Amalio Telenti, Dr. Manfredo Quadroni, Michel A. Duchosal, Prof. Dr. Philippe Schneider, Prof. Dr. Jean-Daniel Tissot

Chapter 15:
Modifications of Host Cell Proteome Induced by Herpes Simplex Virus Type 1 (p 263-283)
Dr. Anna Greco, Dr. Yohann Couté, Dr. Stéphane Giraud, Dr. Jean-Jacques Diaz

Chapter 16:
Francisella Tularensis (p 285-313)
Dr. Jirí Stulík, Martin Hubálek, Lenka Hernychová, Jana Havlasová, Juraj Lenco, Ales Macela, Igor Golovliov, Anders Sjöstedt

Part VI: Central Nervous System
Chapter 17:
Proteomics in Clinical Neuroscience (p 315-340)
Pierre R. Burkhard, Dr. Jean-Charles Sanchez

Chapter 18:
Human Cerebrospinal Fluid (p 341-353)
Dr. Pia Davidsson, Dr. Michael G. Harrington

Chapter 19:
Proteomic Applications for Molecular Assessment of Alzheimer's Disease (p 355-370)
Dr. Odile Carrette, Pierre R. Burkhard, Prof. Dr. Denis F. Hochstrasser, Dr. Jean-Charles Sanchez

Part VII: Mass Spectrometry and Bioinformatics
Chapter 20:
MALDI-MS Imaging in Biomedical Research (p 371-388)
Dr. Markus Stoeckli, Dr. Terry B. Farmer

Chapter 21:
Protein Variations: Resources and Tools (p 389-422)
Dr. Yum Lina Yip, Dr. Maria Livia Famiglietti, Elisabeth Gasteiger, Prof. Dr. Amos Bairoch