CD24分子
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CD24 分子
CD24
常用单克隆抗体或代号: BA- 1,ALB9
主要表达细胞: B,G [B]
分子质量(kDa)和结构: gp35- 45(GPI连接)
功 能: B细胞增殖和分化,结合CD62P,共刺激分子
CD24
Promotes antigen dependent proliferation of B cells; prevents differentiation into plasma cells
Expressed at high levels in small cell lung carcinoma
Positive staining (normal): all B cells, granulocytes, kidney cells, epithelial cells
Positive staining (disease): carcinomas, most pre-B ALL/LBL, virtually all B cell lymphomas
Negative staining: plasma cells, multiple myeloma, T cells, monocytes, red blood cells, platelets