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Combining Uncaging Techniques with Patch-Clamp Recording and Optical Physiology

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Patch-clamp recording is a powerful approach to monitoring membrane electrical activity with high temporal resolution. However, the spatial resolution of patch-clamp recording in a distributed structure such as a neuron or a brain slice is limited by the fact that each electrode records from just one point, making recording from more than a very small number of points impractical.
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