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Determination of Hepatitis C Virus-Specific CD4+ T-Cell Activity in PBMC

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T-cells are the key players in the field on which the virus and the immune response try to defeat or at least control each other. Two categories of T-cells are involved: CD4+ and CD8+ T-cells. CD4+ and CD8+ T-cells have different characteristics and functions and different roles in the immune response to viruses. This chapter discusses methods to determine the CD4+ T-cell activity.
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