17 Genotyping STR Loci Using an Automated DNA Sequencer
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This introduction is intended to inform the forensic scientist of the historical development of STR typing on automated sequencers, as these precedents will have a bearing on the techniques and equipment used in the present-day laboratory. The section then concludes with a brief outline of the principle of a typical automated STR assay, which applies to all of the machines described. Equipment from other manufacturers operates on a similar basis, with the exception of the multi-fluor technique: other means are adopted for the provision of a suitable size standard on single-dye sequencers.